National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

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Partnerships with this Institute

Key Initiatives, Research Partners

This groundbreaking initiative expands the science of targeted medicine. The study of biomarkers creates the potential to individualize medical treatment by determining how a drug works in the body and identifying patients likely to respond to targeted medicines and therapies.

Programs in Development

This kidney safety project will impact public health by generating the data needed to advance, among the scientific community, clinicians and regulators the acceptance of the new biomarkers that are appropriate for monitoring kidney safety in the clinic and from reaching alignment on how these biomarkers should be used to improve clinical diagnoses of drug-induced acute kidney injury (AKI) during drug development and during patient therapy with presently marketed and well known nephrotoxic drugs.

Completed Programs, Past Programs

To best benefit the hundreds of thousands of patients who rely upon life-sustaining kidney dialysis, this program supports the implementation of randomized clinical trials of daily in-center and home hemodialysis.

Program, Research Partners

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) created the Drug-Induced Liver Injury Network to collect and carefully analyze cases of liver injury caused by prescription and non-prescription drugs, nutritional supplements and herbal remedies.