Buprenorphine/naloxone is a treatment system for opiate addiction. This study, overseen by the National Institute on Drug Abuse (NIDA), compares buprenorphone/naloxone and methadone, a synethetic opiate that is also used in the treatment of opiate addicts. It is expected to determine the effect of both treatment systems on liver enzymes and identify risk factors that contribute to liver injury or dysfunction. The Foundation for NIH raised $1.9 million from the private sector for this project.

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