Mental Health

Mental Health

In any given year, one in four Americans suffers from a mental illness. It is a major burden on individuals and society; in fact, the direct and indirect costs of mental illness may top $270 billion annually. Effective treatments have been elusive for many disorders, but research continues to illuminate new possibilities.

Program

Psychiatric GWAS Consortium

The overarching goal of the consortium is to conduct a rigorous set of analyses of GWAS data for Attention Deficit Hyperactivity Disorder, autism, bipolar disorder, major depression disorder, and schizophrenia, utilizing the knowledge and capabilities of the contributing groups to accomplish analyses that can help move the entire field of mental health genetic research forward.

Program

Measures for Clinical Trials of Treatment of Cognitive Impairment (MATRICS-CT)

Schizophrenia is a chronic, severe brain disorder that affects over one percent of the U.S. population. Because many sufferers have difficulty holding a job or caring for themselves, the burden on their families and society is significant. Current treatments fall short of relieving many symptoms.

Past Programs

Genetic Association Information Network (GAIN)

In 2007, the Genetic Association Information Network (GAIN) completed an ambitious program to genotype existing research studies in six major common diseases, and combine the results with clinical data to create a significant new resource for genetic researchers.

Past Programs

Schizophrenia Metabolic Initiative (SMI)

The goal of this multi-year project is to evaluate schizophrenia medications as they relate to indicators for cardiovascular disease and disease stability, and to determine treatment effectiveness.

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