JW Marriott Hotel
1331 Pennsylvania Avenue, NW
Washington, DC 20004

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Cognitive Aging Summit II Part 1: Opening Remarks through Session III
Cognitive Aging Summit II Part 2: Session IV through Closing Remarks

This summit brought together a range of experts in a variety of research fields to discuss the most cutting edge advances in our understanding of age-related brain and behavioral changes. Links to presenter slides are below; a video of the Summit will be available shortly.
 
Made possible by a generous grant from the McKnight Brain Research Foundation, and organized by the National Institute on Aging in partnership with the Foundation for NIH, the event built on the inaugural Cognitive Aging Summit, held in 2007. That first summit identified recommendations for research directions, ultimately leading to the Research Partnership in Cognitive Aging, a partnership between the McKnight Brain Research Foundation and the National Institute on Aging, coordinated by the Foundation for NIH, which funds 17 research grants with a total of $28 million. The five-year grants are aimed at expanding understanding of how people think, learn and remember with age, and at developing interventions to maintain cognitive health as people grow older.

Plenary Speaker

Download speaker presentation: Cognitive Aging: What Do We Know? What's Next? (Power Point), by Carol Barnes, Ph.D., University of Arizona

Session 1: Mechanisms of Age-related Cognitive Change/Targets for Intervention: Genetics/Epigenetics

Download presentation: DNA Methylation in Memory Formation (Power Point), by David Sweatt, Ph.D., University of Alabama-Birmingham

Download presentation: MicroRNAs and Synaptic Plasticity (Power Point), by Kenneth Kosik, MD, University of California-Santa Barbara

Download presentation: Histone Acetylation and Histone Deacetylases in Mouse Models of Neurodegeneration (Power Point), by Li-Huei Tsai, Ph.D., Massachusettes Institute of Technology

Download presentation: Histone Acetylation and Human Cognitive Aging (Power Point), by Scott Small, MD, Columbia University College of Physicians & Surgeons

Download discussant presentation- Naftali Raz, Ph.D., Wayne State University (Power Point)

Download discussant presentation - Peter Rapp, Ph.D., National Institute on Aging (Power Point)

Session II: Mechanisms of Age-related Cognitive Change/Targets for Intervention: Neural Circuits/Networks/Plasticity

Download presentation: Synaptic Correlates of Cognitive Performance: Implications for Cognitive Aging (Power Point), by John Morrison, Ph.D., Mt. Sinai School of Medicine

Download presentation: Why CRUNCH Matters: Compensation-Related Utilization of Neural Circuits, Aging, and Intervention (Power Point), by Patricia Reuter-Lorenz, Ph.D., University of Michigan

Download presentation: Dorsolateral Prefrontal Cortex Dysfunction Associated with White Matter (Power Point), by Charles DeCarli, MD, University of California-Davis

Download presentation: Age and Amyloid Related Alterations in Memory Networks: More or Less? (Power Point), by Reisa Sperling, MD, Brigham and Women's Hospital, Massachusetts General Hospital, and Harvard Medical School

Download discussant presentation - Clinton Wright, MD, University of Miami (Power Point)

Download discussant presentation- Claudia Kawas, MD, University of California-Irvine (Power Point)

Session III: Mechanisms of Age-related Cognitive Change/Targets for Intervention: Inflammatory, Oxidative and Metabolic Processes

Download Presentation: Microglial Priming, Neuroinflammation, and Susceptibility to Peripheral Inflammation-Induced Cognitive Decline with Aging (Power Point), by Steven Maier, Ph.D., University of Colorado

Download Presentation: Linking Oxidative Stress of Aging to the Senescent Neurophysiology of Cognitive Decline (Power Point), by Thomas Foster, Ph.D., University of Florida

Download Presentation: The Role of Insulin in Normal and Pathological Brain Aging (Power Point), by Suzanne Craft, Ph.D., University of Washington

Download Presentation: Obesity, Metabolic Syndrome, and Cognitive Aging: Population Based Studies (Power Point), by Kristine Yaffe, MD, University of California-San Francisco

Download discussant presentation - Susan Resnick, Ph.D., National Institute on Aging (Power Point)

Download discussant presentation - Philip Landfield, Ph.D., University of Kentucky (Power Point)

Session IV: Mechanisms of Age-Related Cognitive Change/Targets for Intervention: Social Interactions/Stress

Download presentation: Psychosocial Influences on Cogntive Aging (Power Point), by Robert Wilson, Ph.D., Rush University

Download presentation: Stress and Cognitive Aging (Power Point), by Martin Silwinski, Ph.D., Pennsylvania State University

Download presentation: A Long-Term Behavior Genetics View of Stress and Cognitive Aging (Power Point), by William Kremen, Ph.D., University of California-San Diego

Download presentation: Altering the Stress Response with Neuronal Gene Therapy (Power Point), by Robert Sapolsky, Ph.D., Standford University

Download discussant presentation: Margie Lachman, Ph.D., Brandeis University (Power Point)

Download presentation by Molly Wagster, Ph.D., and Jonathan King, Ph.D., National Institute on Aging (Power Point)

Session V: Considerations in Design

Download presentation: Cognitive Aging and Translational Research: Strategies to Sustain Neurological Function While Aging (Power Point), by Roberta Brinton, Ph.D., University of Southern California

Download presentation: Biomarker for Aging Studies: What Have We Learned from AD?  (Power Point), by Ronald Petersen, Ph.D, MD, Mayo Clinic College of Medicine

Download presentation: Measurement Matters: Evaluating Interventions to Prevent Cognitive Decline (Power Point), by Dan Mungas, Ph.D., University of California-Davis

Download presentation: FDA Perspective on Approval of Drus for Age-Related Cognitive Decline (Power Point), by Russel Katz, MD, Food and Drug Administration

Session VI: Clinical Trials: New Opportunities

Download Presentation: The Clinical Study as Experiment: Testing a Pivotal Hypothesis (Power Point), by Michela Gallagher, Ph.D., Johns Hopkins University

Download Presentation: Guanfacine for Prefrontal Executive Dysfunction in Healthy Aging  (Power Point), by Christopher van Dyck, MD, Yale University

Download Presentation: Behavioral and Dietary Interventions Synergize to Promote Successful Aging  (Power Point), by Carl Cotman, Ph.D., University of California-Irvine

Download Presentation: Exercising the Mind and Body: Aging and Brain Health  (Power Point), by Sandra Chapman, Ph.D., University of Texas-Dallas

Discussant - Howard Fillit, MD, Alzheimer's Drug Discovery Foundation (Power Point)